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testxlog

On the road of chemotherapy, I have always been worried about when platinum resistance will lead to no drugs available, but I never expected to have an allergy before developing resistance.

  • Originally thought that the experience summarized during 9 chemotherapy sessions for cancer was already quite comprehensive
  • However, never expected that during the 10th chemotherapy session, there would be a platinum allergy, specifically Carboplatin allergy
  • The worries did not come true
    • Worries about when Carboplatin will develop resistance
    • Carboplatin resistance often leads to potential cross-resistance with other platinum drugs
    • This means that platinum-based chemotherapy can no longer be used
    • Only targeted therapy, immunotherapy, etc., can be used for maintenance
  • Unexpectedly happened
    • Carboplatin allergy during the 10th chemotherapy session
    • Allergy indicates that platinum drugs are still effective
    • Research has found that Carboplatin allergies often occur between the 6th and 21st chemotherapy sessions
    • Professor Markman and others found that about 27% of patients will develop an allergy after the 7th Carboplatin chemotherapy session
    • So now I understand that the appearance of an allergy is just a matter of time
    • Allergy is still better than resistance
    • Consider switching to other platinum drugs such as Oxaliplatin next time
  • Persistence is victory
    • I hope for some relief in bone marrow suppression
    • I hope to endure a few more cycles of chemotherapy
    • I hope to see signs of improvement or even cure in CT images and tumor markers
    • Everything is hope, having hope is always better than having none
  • photo by Yosuke Ota on Unsplash
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